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Description: Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 µg/ml. Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the treatment of inflammatory skin conditions.
Name: Clobetasol Propionate-d5
CAS#: 2280940-18-1
Chemical Formula: C25H27D5ClFO5
Exact Mass: 471.2236
Molecular Weight: 472.0049
Elemental Analysis: C, 63.62; H, 7.90; Cl, 7.51; F, 4.03; O, 16.95
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